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Puromycin Dihydrochloride

Puromycin Dihydrochloride

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商品描述
Puromycin Dihydrochloride,HY-B1743A ,MCE：
Description

Aminoguanidine hydrochloride is a diamine oxidase and NO synthase inhibitor, reduces levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone, is an investigational drug for the treatment of diabetic nephropathy.

Clinical Trial
NCT Number Sponsor Condition Start Date Phase
NCT00184990 Radboud University Endotoxemia January 2005 Phase 1
NCT00159380 Imperial College London Asthma September 2003 Not Applicable
NCT02099981 University of Minnesota - Clinical and Translational Science Institute Diabetic Retinopathy July 2016 Phase 1
NCT00180635 Imperial College London Healthy Volunteers (Non-smoker)|Healthy Volunteers (Smoker)|Chronic Obstructive Pulmonary Disease October 2003 Not Applicable
Solvent & Solubility
In Vitro: 

H2O : ≥ 43 mg/mL (388.96 mM)

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.0457 mL 45.2284 mL 90.4568 mL
5 mM 1.8091 mL 9.0457 mL 18.0914 mL
10 mM 0.9046 mL 4.5228 mL 9.0457 mL
*Please refer to the solubility information to select the appropriate solvent.


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