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Human IL-7

Human IL-7

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商品描述
 Human IL-7 ，130-095-363，MiltenyiBiotec:
overview：
IL-7 stands for interleukin 7. Human IL-7 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human IL-7 can be used for a variety of applications, including:
  • In vitro T cell expansion.
  • In vitro T cell priming.
  • In vitro differentiation of T cells and iNKT cells.
  • Investigation of IL-7 mediated signaling pathways


Details:

Background information

IL-7 is a member of the type I cytokine family. The primary sources of IL-7 are non-hematopoietic stromal cells in bone marrow, thymus, and lymphoid organs and tissues. It is a pleiotropic cytokine with central roles in modulating T cell development and peripheral T cell homeostasis. IL-7 can act both as a T cell growth factor as well as a critical anti-apoptotic survival factor for naive and memory T cells. IL-7 is related to IL-2 and signals through a heterodimeric receptor composed of the common cytokine signaling γ-chain and IL-7 receptor α-chain.

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.
Premium-grade
cytokines offer the convenience of high and well-defined biological activities and allow exact unit dosing for demanding applications. The biological activity is determined after lyophilization and reconstitution, and normalized to WHO/NIBSC standards whenever available. In general, endotoxin levels are <0.01 ng/μg (<0.1 EU/μg), and purities are >97%. Lot-specific certificates of analysis are available on request (macstec@miltenyibiotec.de).

Biological activity

  • Proliferation of 2E8 cells (NIBSC 90/530)
  • premium grade: ≥ 5×
    10
    7
    U/mg
    (typical activity: ≥ 1.5×
    10
    8
    U/mg
    )
  • research grade: ≥ 2×
    10
    7
    U/mg
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規(guī)格型號
M/MiltenyiBiotec
130-042-201
MS Columns
25個
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MACS MultiStand
1 piece
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LS Columns
25 columns
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CD45 MicroBeads, human
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CD34 microbead kit
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Anti-Mouse IgG MicroBeads
2ml
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Anti-PE MicroBeads
1kit
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CD14 MicroBeads, human
1kit
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CD56 MircroBeads,human
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CD235a (Glycophorin A) MicroBeads, human
1kit
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Dead Cell Removal Kit
1kit
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130-090-433
IFN-γ Secretion Assay – Detection Kits, human
100T
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QuadroMACS Separator
1 piece
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130-091-051
QuadroMACS Starting Kit (LS)
1kit
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130-091-052
MACS 15 mL Tube Rack
1PK
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130-091-221
autoMACS Rinsing Solution
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autoMACS Rinsing Solution
6×1.45L
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MACS BSA Stock Solution
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μ Columns with plungers
1kit
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130-111-573
Exosome Starting Kit CD9, human
1kit
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200-074-400
Freezing Bags
24 bags
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200-074-401
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