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Rottlerin, Kinase inhibitor (ab120377)

Rottlerin, Kinase inhibitor (ab120377)

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商品描述
  • Product name
    Rottlerin, Kinase inhibitor
  • Description
    Kinase inhibitor
  • Biological description
    Originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Also inhibits MAPKAP-K2 and PRAK (IC50 values are 5.4 and 1.9 μM, respectively), CHK2, PLK1, PIM3 and SRPK1.
  • Purity
    > 95%
  • Chemical name
    3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone
  • Molecular weight
    516.55
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C30H28O8
  • CAS Number
    82-08-6
  • PubChem identifier
    5281847
  • Storage instructions
    Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CC(=O)c4c(O)c(Cc2c(O)c(c1OC(C)(C)C=Cc1c2O)C(=O)/C=C/c3ccccc3)c(O)c(C)c4O
  • Source

    Synthetic